BIOM20001 Molecular and Cellular Biomedicine GENETICS NOTES

Description

Comprehensive MCB notes for GENETICS! - Includes contents and page numbers for easy navigation Topics included: Genome, chromosome & gene - What is a genome? - What is a gene - Pseudogenes - Repetitive elements - Chromatin structure - Origins of replication - Telomeres - Centromeres - Transcription: RNA pol - Transcription: initiation - Transcription: elongation and termination - Splicing - Genetic code - Translocation Gene regulation - General principles - Ligand-regulated DNA binding - Prokaryotic gene regulation - Lac operon - Eukaryotic gene regulation - Globin gene regulation - Globin gene mutations & disease - Epigenetics Cancer - Introduction to cancer - Oncogenes and tumour suppressors - DNA damage and repair - Oncogene examples - P53 - Metastasis - Cancer progression - Epigenetics Development - Introduction to development - Key concepts of development - Drosophila segment hierarchy - Hox genes - Model organisms - DNA sequencing - Human genome projects - Personal genomics - Frontiers of genetics in human health