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Organic Chemistry Paperback – 20 July 2000

4.6 out of 5 stars 141 ratings

A new style of textbook, aimed principally at the European (and British in particular) student. It is needed because almost all current organic chemistry texts are written to a fixed American pattern. This text is different from these in a number of important ways: The approach is based on explanation rather than fact. The functional group approach (alkane, alkene, alkyne) has served American State College readers well but increasingly students and instructors are attracted more to an approach based on mechanism and reaction type. This approach aims at understanding rather than factual knowledge and, though slower at the start, eventually gives the student power to understand compounds and reactions never previously encountered. This is a big advantage in a science already too large for individuals to learn and which is annually expanding at an ever greater rate. The basics of the subject are explained carefully and thoroughly. How to draw molecules realistically and how to draw mechanisms to reveal the fundamental chemistry are both emphasised. Important points are revisited when they become relevant in later chapters. Examples are very important too. New examples are given each time a concept resurfaces, and examples from everyday life and medicinal chemistry are frequently used. The authors want the readers to be excited by the universality of organic chemistry rather than be overwhelmed by facts. The design of the book has features to help comprehension. Structures are drawn in red, and black is used on them for emphasis. Other colours are used flexibly to draw attention to atoms, molecules, orbitals, arrows or whatever the authors want to emphasise rather than being used in a rigid systematic way. There are four types of "box" used to separate material from the main text, ranging from extra important summaries to diversions which can be omitted at first reading. The early chemistry chapters feature carbonyl group reactions because addition to carbonyl groups is probably the easiest reaction to understand. Thereafter the chemistry develops in a logical sequence but chapters on spectroscopy, stereochemistry etc are interspersed among those dealing with chemical reactions. From time to time review chapters summarise what has been described in a particular area. A personal and honest approach is adopted. The authors write clearly and directly to the reader, sharing their enthusiasms, understandings and doubts. If they believe an explanation is imperfect or controversial, they say so. They show that organic chemistry is developing rapidly, and that new ideas continually emerge to replace the old. The authors know from experience what conceptual difficulties often overwhelm students at an early stage in their studies and they devote more space to these points, give more examples, and revisit them when they can be applied. The aim is to help the readers master these points for themselves rather than just learn them off by heart.

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Organic Chemistry
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Review

'If you want a really good book about organic chemistry get "Organic Chemistry" by Clayden, Greeves, Warren & Wothers' Christian Aichinger, Organic Chemistry Blog

What strikes the reader straight away is the way the text is laid out so that it is visually exciting. ...I could go on, so let me end by congratulating the authors and publishers in producing what I am sure will become the standard text in organic chemistry. Perhaps I should just summarise how I felt about the book when I came to put it down: refreshing, exciting and motivational. Tony Barrett, Imperial College London

"The authors should be congratulated for compiling a book that should prove very popular with our students...the text is very comprehensive and covers key areas in a very attractive and user friendly way. Thank you to OUP for publishing the book at a really good price". Dr Don Green, University of North London.

Product details

  • Publisher ‏ : ‎ OUP Oxford (20 July 2000)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 1536 pages
  • ISBN-10 ‏ : ‎ 0198503466
  • ISBN-13 ‏ : ‎ 978-0198503460
  • Dimensions ‏ : ‎ 21.84 x 5.33 x 27.69 cm
  • Customer Reviews:
    4.6 out of 5 stars 141 ratings

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Stuart G. Warren
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  • maulibe
    5.0 out of 5 stars il miglior libro per chimica organica
    Reviewed in Italy on 19 September 2022
    Verified Purchase
    credo che sia il miglior libro di chimica organica, non c'`e bisogno di una conoscenza di inglese molto elevata ma basta una conoscenza base per renderlo leggibile
    Report
  • ManuelReyes
    4.0 out of 5 stars Organic Chemistry - Clayden
    Reviewed in Spain on 30 December 2018
    Verified Purchase
    El libro llegó en buenas condiciones. Es de segunda mano pero está prácticamente perfecto.

    Muy buena compra, vendedor muy recomendable.
  • chemstudent
    5.0 out of 5 stars Good Organic Text
    Reviewed in the United States on 15 January 2012
    Verified Purchase
    As a note, this review is based only on the first 5 chapters and ch. 30 (retrosynthetic analysis). Compared to the plethora of organic texts out there, clayden's organic chemistry certainly is a good alternative for use in an intro organic class that more instructors should consider. While some reviewers have noted that they used this book as review, I am sure that this could also be used by those who have never taken organic chemistry before as the authors writing is clear and easy to read.

    This text along with loudon's text are the most affordable when priced with their sol. manuals and both are well written. Compared to loudon, clayden et al. take a different approach in presenting the topics typically covered in more traditional organic texts such as those by mcmurry, solomons, and carey. So instructors that choose to use this book will have to select which chapters to cover rather than in other books where you can typically just go in order from say Ch. 1- 12 for first semester then Ch 13 - 25 in the second semester. There are also many areas/ more modern reactions not typically covered in intro organic that some instructors may also wish to cover that may be more their area of expertise such as organometallics. In addition, there are many interesting examples to be found in this book when discussing each particular topic.

    Pros are that it's a relatively easy read and mechanisms are clearly depicted. The only cons I found are 1) that it resembles a large phonebook in that it is paperback and quite heavy to lug around. 2) The authors choice of using red excessively in diagrams and to highlight important points to me is rather unpleasant, but that's just me. 3) there are limited number of problems at the end of each section. My opinion is that to really succeed in learning organic chemistry, you have to be able to practice drawing products, reaction mechanisms, etc to really retain the material and this book just doesn't offer enough problems for the typical undergrad to practice to feel confident before an exam. 4) There are too many notes/text boxes on the side. This is distracting when reading and some can probably be included in the main text rather than relegated to the page margins. 5)There is no summary at the end of each chapter of the reactions covered.

    While I have listed many of the cons, I don't think they necessarily detract the substantial content in this book.
    In this regard, I believe that the 2nd ed. is to be expected sometime this year and I think it will be as much of a success as the 1st ed.
  • TheReader
    5.0 out of 5 stars Umfangreich, interessant, detailliert
    Reviewed in Germany on 10 August 2009
    Verified Purchase
    Den Autoren ist ein sehr guter Wurf gelungen. Inhaltlich sehr ansprechend erläutert und illustriert sowie vom Inhalt her sehr ausführlich dargestellt, wird sich dieses Werk gewiss schnell als eines der Standardwerke etablieren können. Wenngleich allenortens übermächtig verwendete knallrote (Halb-)Strukturformeln nicht wirklich modernen wahrnhemungspsychologischen Aspekten genügen. Da ist der Vollhardt tatsächlich in seiner Farbgebung dezenter. Dennoch: alle Themen werden im Clayden interessant und kompetent präsentiert und Reaktionsverläufe mechanistisch sehr gut dargestellt. Ein tolles Buch für alle OC-Interessierten. Der doch etwas zu flexible Einband und das große Format erlauben kein einfaches Handling dieses dicken Wälzers und dürfte zu schnellem Verschleiß führen.

    Anmerkung: Dass "der Clayden" im Vergleich zum Vollhardt/Shore um Längen besser wäre, kann ich nicht feststellen. Auch ist der Vollhardt in seiner aktuellen Ausgabe und sogar im Hardcover !!! gerade einmal 8,- € teurer, bei vergleichbaren 1300 Seiten Umfang. Inhaltlich sind beide Werke vergleichbar, keines lässt wichtige Themen aus oder vernachlässigt grundlegende Aspekte. Den Vollhardt gibt es indes schon seit 20 Jahren und gehört - zu Recht - zu den führenden und ausgereiften Werken in der OC. Zum Teil gab es sogar eine CD-ROM mit Chemie-Software dazu. Es scheint aber eine Eigenart von Studenten zu sein, zu glauben, dass in jedem Chemie-Hauptfach immer nur ein einziges Buch ausreicht oder ausreichen muss, um sein Vordiplom zu bekommen. So funktioniert es nicht! Eine solide Kenntnis mehrerer Werke zahlt sich später definitiv aus. So wie sich Wedler und Atkins in PC ergänzen, so passen auch Vollhardt und Clayden zusammen und ergänzen sich. Aber auch das OC-Buch von Allinger, Cava, De Jong steht trotz seines betagten Alters einem Clayden inhaltlich in nichts nach. Die Aufmachung ist mittlerweile natürlich bunter und moderner, aber das Fachliche bleibt gerade bei den Grundlagen ziemlich konstant.
  • Max
    5.0 out of 5 stars The ultimate organic textbook!
    Reviewed in the United Kingdom on 20 June 2014
    Verified Purchase
    The most thorough and well written organic chemistry textbook out there. This book is absolutely essential for an undergraduate organic chemistry course as it covers:

    1) What is Organic Chem.?
    2) Organic Structures
    3) Determining organic structure
    4) Structure of molecules
    5) Organic reactions
    6) Nucleophilic addition to the carbonyl group
    7) Delocalisation and conjugation
    8) Acidity, basicity and pka
    9) Organometallic reagents for c-c bonds
    10) Conjugate addition
    11) Proton NMR
    12) Nucleophilic substitution at the carbonyl group
    13) Equilibria, rates and mechanisms
    14) Nucleophilic substitution at carbonyl with loss of oxygen
    15) Review of spectroscopic methods
    16) Stereochemistry
    17) Nucleophilic substitution at saturated carbon
    18) Conformational analysis
    19) Elimination reactions
    20) Electrophilic addition to alkenes
    21) Formation of reactions of enols and enolates
    22) Electrophilic aromatic substitution
    23) Electrophilic alkenes
    24) Chaemoselectivity: selectivity and protection
    25) Synthesis in action
    26) Alkylation of enolates
    27) Reactions of enolates with aldehydes and ketones
    28) Acylation at carbon
    29) Conj. addition of enolates
    30) Retrosynthetic analysis
    31) Controlling the geometry of double bonds
    32) Determination of stereochemistry by spectrscopi methods
    33) Stereoselective reaction of cyclic compounds
    34) Diastereoselectivity
    35) Pericyclic reactions 1: cycloadditions
    36) Pericyclic reactions 2: sigmatropic + electrocyclic
    37) Rearrangements
    38) Fragmentation
    39) Radical reactions
    40) Synthesis and reactions of carbenes
    41) Determining reaction mechanisms
    42) Saturated heterocycles and stereoelectronics
    43) Aromatic heterocycles 1: structure and reactions
    44) Aromatic heterocycles 2: synthesis
    45) Asymmetric synthesis
    46) Organo-main-group chemistry 1: sulfur
    47) Organo-main-group chemistry 2: boron, silicon and tin
    48) Organometallic chemistry
    49) The chemistry of life
    50) Mechanisms of biological chemistry
    51) Natural products
    52) Polymerisation
    53) Organic chemistry today

    Totalling some 1500 pages of material making it a weighty tome.

    Each chapter thoroughly explains the principles with a multitude of illustrated examples to demonstrate each point, references to previous chapters to aid cementing in of the knowledge and references to where it will be key in the future. The end of each chapter has a good set of examples to help you apply the theory but worked answers must be purchased separately. The approach of the authors makes it extremely accessible, to the extent that someone with no prior knowledge could use and learn from it, but is also an excellent text for the more advanced years of your degree (years 3,4 and 5) whereas those offered by McMurry fall short in the latter years

    Some things are a little off as at later times it can linger on smaller points and suffers from some more inaccurate catalytic cycles though this could be more the fault of the literature available on some of the cycles.

    All in all, this is the text you want for an undergrad course but at the same time is a brilliant reference text for once you have finished and go into industry or further education.