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Robert A. Weinberg
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The Biology of Cancer Paperback – 7 June 2006

by Robert A Weinberg (Author), Robert A. Weinberg (Author)
4.7 4.7 out of 5 stars 82 ratings
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The Biology of Cancer
The Biology of Cancer
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The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology.

The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The book includes many recent and topical references, and is intended to empower the student to move directly into the primary research literature.

The text is up-to-date and provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes. The Biology of Cancer provides insights into many aspects of immunology, developmental biology, and neurobiology.

The exceptional full-color art program contains many images published for the first time. The book is extensively illustrated with schematic drawings, micrographs, computer-generated models and graphs. The pieces were chosen to support and clarify the concepts, as well as to supply additional interest.

Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories, and for clinical professionals.

Previous page
  1. Print length
    864 pages
  2. Language
    English
  3. Publisher
    Garland Science
  4. Publication date
    7 June 2006
  5. Dimensions
    20.96 x 2.54 x 26.67 cm
  6. ISBN-10
    0815340761
  7. ISBN-13
    978-0815340768
  8. See all details
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Product description

Review

This is an impressively thoughtful, beautifully balanced analysis of where we stand today in the critical attempt to understand, and thereby defeat cancer as a scourge on humanity. Not only is it the perfect text for a serious course on cancer biology, it should be read by every cancer researcher - Bruce Alberts, University of California, San Francisco, USA

The Biology of Cancer is no doubt the definitive statement on its topic today. -Science, 11 August 2006: Vol. 313. no. 5788

There is no comparable text in cancer biology and no single book that is so current and informative. -Nature, November 30, 2006, Vol 444

'The Biology of Cancer, written by the distinguished American cancer biologist Robert Weinberg, is by far the most extensive of these new works and, as the product of a single author, is a remarkable achievement. The book is beautifully illustrated in full colour and well supplied with key review articles. It is extremely well written in language that should be accessible to the non-expert. Overall, this is a remarkable achievement that is by far the most comprehensive coverage of this field available.' - The Times Higher Education Supplement, February 23rd 2007

"The breadth of the topics covered, the clear writing style, the logical organization and the beautiful figures make The Biology of Cancer a classic text for any biologist interested in cancer...An additional strength of the book is the multimedia CD...¦Thus, The Biology of Cancer is not only a great read but also an outstanding learning tool."-Nature Cell Biology (November 2007) vol. 9, no. 11

About the Author

Dr. Robert A. Weinberg is a founding member of the Whitehead Institute for Biomedical Research and the Daniel K. Ludwig Professor for Cancer Research at the Massachusetts Institute of Technology (MIT). He is an internationally recognized authority on the genetic basis of human cancer.

Dr. Weinberg and his colleagues isolated the first human cancer-causing gene, the ras oncogene, and the first known tumor suppressor gene, Rb, the retinoblastoma gene. The principal goal of his research program is to determine how oncogenes, their normal counterparts (proto-oncogenes), and tumor suppressor genes fit together in the complex circuitry that controls cell growth. More recently, his group has succeeded in creating the first genetically defined human cancer cells. He is particularly interested in applying this knowledge to improve the diagnosis and treatment of breast cancer.

Dr. Weinberg is the author or editor of five books and more than 325 articles. His three most recent books, intended for a lay audience, are "One Renegade Cell", "Racing to the Beginning of the Road: The Search for the Origin of Cancer" and "Genes and the Biology of Cancer," co-authored with Dr. Harold E. Varmus, former Director of the National Institutes of Health. He is an elected Member of the U.S. National Academy of Sciences and Fellow of the American Academy of Arts and Sciences.

Among Dr. Weinberg's many honors and awards are the Discover Magazine 1982 Scientist of the Year, the National Academy of Sciences/U.S. Steel Foundation Award in Molecular Biology, the Sloan Prize of the General Motors Cancer Research Foundation, the Bristol-Myers Award for Distinguished Achievement in Cancer Research, the Harvey Prize from the American Society for Technion Israel Institute of Technology, the Gairdner Foundation International Award, the Keio Medical Foundation Prize, the 1997 National Medal of Science, the City of Medicine Award and the 2004 Wolf Foundation Prize and the Prince of Asturias Science Prize. He has served on scientific advisory boards for the Institute of Molecular Pathology in Vienna, Austria, the Weizmann Institute in Rehovot, Israel, and the Massachusetts General Hospital in Boston.

Born in Pittsburgh in 1942, Dr. Weinberg received his BS (1964) and PhD (1969) degrees in Biology from MIT. He did postdoctoral research at the Weizmann Institute and the Salk Institute in La Jolla, California, and then returned to MIT in 1972. In 1982, he was appointed Professor of Biology at MIT and also became one of the five original Members of the Whitehead Institute. He has been an American Cancer Society Research Professor at Whitehead and MIT since 1985.

Product details

  • Publisher ‏ : ‎ Garland Science (7 June 2006)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 864 pages
  • ISBN-10 ‏ : ‎ 0815340761
  • ISBN-13 ‏ : ‎ 978-0815340768
  • Dimensions ‏ : ‎ 20.96 x 2.54 x 26.67 cm
  • Customer Reviews:
    4.7 4.7 out of 5 stars 82 ratings

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Robert A. Weinberg

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Cliente Amazon
5.0 out of 5 stars Ottimo acquisto!
Reviewed in Italy on 24 October 2016
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Arrivato in perfette condizioni. La descrizione del prodotto è ottima. Libro molto utile per zstudiare tutto quello che riguarda il cancro e i suoi vari pathways molecolari. Ovviamente non è un libro adatto per chi cerca una descrizione approfondita dei diversi tipi di tumori e le diverse diagnosi differenziali.
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Timothy
5.0 out of 5 stars Five Stars
Reviewed in Canada on 13 May 2015
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Love the book but came to me damaged.
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developer1
5.0 out of 5 stars Just Excellent
Reviewed in the United States on 9 February 2012
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(Edit: please note that this review is for the 2007 edition. )

I think this is one of the best written technical books ever. The author is simply a gifted communicator of ideas and knowledge.

Much of the book uses the thread of the history of cancer research to give a perspective on how knowledge of cancer biology was built up, and it helps immensely in terms of organizing the knowledge and remembering it.

The author does an incredible job of going the extra mile to clarify and elucidate the biology. While you would be advised take a molecular biology course before reading this book, even if you don't, a lot of the biological mechanisms are explained so well they almost serve as foundation. And cancer makes a wonderful application for the molecular biology knowledge you acquired from other courses, while serving to reinforce and provide dramatic examples for that knowledge.

The author also knows how to simply keep things interesting with an easy-to-read style, a good sense of "story", and he anticipates most questions that might need explaining.

I'm sure future editions could only get larger in content due to the rapid pace of research. I look forward to anything written on the subject by this author. Perhaps the best strategy would be to try to keep the core book about the same length (of course updating as necessary), and spin off other books that provide depth in narrower areas. I hope the author continues writing more books on the subject.

To be fair, it is probably easier to make a book on cancer biology more interesting than, say, a biochemistry book. But I'd sure like to see a book on biochemistry by this author.

If I were to add anything to the book, it might be to review or summarize the various "drivers" of cancer that are covered (and discovered over the years) throughout the book, so you get a little more clarity on how they interact developmentally. For example, while certain mutations drive cancer, do they also require other cell changes or are they sufficient, etc. I think the answer is well explained if you read carefully, but perhaps a diagram of all the developmental pathways (evolution of cell changes) to uncontrolled cell division could be laid out somehow in one big picture, like a directed graph.
3 people found this helpful
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John
5.0 out of 5 stars One of the best books I have ever read.
Reviewed in the United Kingdom on 11 April 2011
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It's a book for your bookcase there is no doubt about this. The book is written more for graduate students that have good knowledge about molecular biology and cancer. That does not mean that the book is unsuitable for undergraduate students of Medicine or Pharmacy and generaly for Schools of Health Sciences. In last semester, I and my team we made a work for a subject in our School about cancer and especially in Metastasis and Antiangiogenic Drugs. We are undergraduate students and the book was really helpful. I am sure that I am going to use this book again in future as an undergraduate or graduate student. As I said before if you have some basic knowledge of Molecular Biology it would be easier to study and understand the complicated Biology of Cancer. Personally I bought this book from Amazon, which arrived in excellent condition and in estimated date. If you are a student of Medicine or Pharmacy, and if you are interested in cancer I recommend this book undoubtably. Is the ''BIBLE'' of Cancer.
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Darth Vader
5.0 out of 5 stars 勉強会に最適です
Reviewed in Japan on 17 January 2013
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改訂されるごとに詳細な部分のUp-to-dateな情報が加わったりしています。

ですがベースとなる腫瘍に対する根源的な概念は変わらず半永久的な名著といえます。

僕の所属するラボでは毎週、院生を中心にしてチャプターごとに輪読会をしていますが、英語版（原著）では図のCD-ROMが付録についているので、英語に自信がある方は是非こちらのご購入お勧めします!!!

EMT、ニッチ、癌幹細胞の説明部分がやはりもっともインパクトありですね。AACRでの講演もOpen Accessなので是非聴いてみましょう
3 people found this helpful
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