UNSW

Semester 2, 2016


HD CHEM1021 Notes Part 1: Analytical chemistry

71 pages

8,377 words

$29.00

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Description

These notes cover the first three topics normally taught in CHEM1021: chemical kinetics, stereochemistry and spectroscopy.

Throughout, I have included my own worked solutions to relevant questions written as part of study and during exam preparation.

My CHEM1021 mark: 92 (HD)

Analytical chemistry

Chemical kinetics:
- What is kinetics?
- Definition of rate
- Working with reaction rates
- The general case
- Measuring reaction rates
- Factors affecting reaction rate
- Quantifying rates - rate equations
- Worked examples with orders of equations
- Experimental determination of rate equations
- Differential and integrated forms of the rate equation
- Reactant half-lives
- Effect of temperature on reaction
- Reaction mechanisms
- Multi-step reactions and activation energies
- Catalysis: heterogeneous and homogeneous
- Enzyme catalysis

Stereochemistry:

- Representations of organic molecules
- Molecular shape
- Revision of bonding – sp3 hybridisation
- Conformers
- Functional groups
- The special case of benzene/aromatic groups
- Nomenclature: alkanes
- What are isomers?
- Hydrocarbons
- Structural isomers
- Stereoisomers
- Enantiometers
- Chiral vs achiral
- Properties of enantiomers
- Optical activity
- Naming enantiomers
- Cahn-Ingold-Prelog Rules
- Examples of CIP rules
- The thalidomide story
- More than one stereocentre
- Enantiomers and diastereomers
- Amino acids
- Double bonds – sp2 hybridisation
- Lack of rotation is important
- Defining this form of stereochemistry
- Assigning E/Z isomers
- Inorganic stereoisomers

Spectroscopy:
- Structural determination
- Elemental analysis
- How can we use energy sources to reveal molecular information?
- What is spectroscopy? What are spectra?
- Direct structure determination: x-ray crystallography
- What if it’s not a high-quality crystal?
- Mass spectrometry
- Other info from mass spectrometry
- Other spectroscopic techniques
- UV-Visible spectroscopy
- So, what info do you get from UV-vis spectroscopy?
- Infrared spectroscopy
- What info do you get from IR spectroscopy?
- Nuclear magnetic resonance spectroscopy
- NMR active nuclei
- 1H NMR Information
- Chemical shift
- Signal integrals
- Magnetic resonance imaging (MRI)
- Multiplicity
- Interpreting NMR spectra – different functional groups